{"intvolume":"       233","publication_identifier":{"issn":["00224804"]},"quality_controlled":"1","publication":"Journal of Surgical Research","date_created":"2023-06-15T13:02:39Z","date_updated":"2023-08-18T11:54:15Z","user_id":"245590","page":"207-212","keyword":["Intra-abdominal hypertension","Suture tension","Laparotomy closure","Incisional hernia","Ruptured abdomen","Implantable sensor"],"author":[{"first_name":"Alexander","last_name":"Schachtrupp","full_name":"Schachtrupp, Alexander"},{"last_name":"Wetter","orcid":"0000-0003-3223-5050","full_name":"Wetter, Oliver Utz","id":"206920","first_name":"Oliver Utz"},{"full_name":"Höer, Jörg","last_name":"Höer","first_name":"Jörg"}],"publisher":"Elsevier BV","doi":"10.1016/j.jss.2018.07.043","_id":"3229","status":"public","title":"Influence of Elevated Intra-abdominal Pressure on Suture Tension Dynamics in a Porcine Model","publication_status":"published","type":"journal_article","year":"2019","citation":{"alphadin":"<span style=\"font-variant:small-caps;\">Schachtrupp, Alexander</span> ; <span style=\"font-variant:small-caps;\">Wetter, Oliver Utz</span> ; <span style=\"font-variant:small-caps;\">Höer, Jörg</span>: Influence of Elevated Intra-abdominal Pressure on Suture Tension Dynamics in a Porcine Model. In: <i>Journal of Surgical Research</i> Bd. 233, Elsevier BV (2019), S. 207–212","chicago":"Schachtrupp, Alexander, Oliver Utz Wetter, and Jörg Höer. “Influence of Elevated Intra-Abdominal Pressure on Suture Tension Dynamics in a Porcine Model.” <i>Journal of Surgical Research</i> 233 (2019): 207–12. <a href=\"https://doi.org/10.1016/j.jss.2018.07.043\">https://doi.org/10.1016/j.jss.2018.07.043</a>.","mla":"Schachtrupp, Alexander, et al. “Influence of Elevated Intra-Abdominal Pressure on Suture Tension Dynamics in a Porcine Model.” <i>Journal of Surgical Research</i>, vol. 233, Elsevier BV, 2019, pp. 207–12, doi:<a href=\"https://doi.org/10.1016/j.jss.2018.07.043\">10.1016/j.jss.2018.07.043</a>.","short":"A. Schachtrupp, O.U. Wetter, J. Höer, Journal of Surgical Research 233 (2019) 207–212.","bibtex":"@article{Schachtrupp_Wetter_Höer_2019, title={Influence of Elevated Intra-abdominal Pressure on Suture Tension Dynamics in a Porcine Model}, volume={233}, DOI={<a href=\"https://doi.org/10.1016/j.jss.2018.07.043\">10.1016/j.jss.2018.07.043</a>}, journal={Journal of Surgical Research}, publisher={Elsevier BV}, author={Schachtrupp, Alexander and Wetter, Oliver Utz and Höer, Jörg}, year={2019}, pages={207–212} }","ieee":"A. Schachtrupp, O. U. Wetter, and J. Höer, “Influence of Elevated Intra-abdominal Pressure on Suture Tension Dynamics in a Porcine Model,” <i>Journal of Surgical Research</i>, vol. 233, pp. 207–212, 2019.","ama":"Schachtrupp A, Wetter OU, Höer J. Influence of Elevated Intra-abdominal Pressure on Suture Tension Dynamics in a Porcine Model. <i>Journal of Surgical Research</i>. 2019;233:207-212. doi:<a href=\"https://doi.org/10.1016/j.jss.2018.07.043\">10.1016/j.jss.2018.07.043</a>","apa":"Schachtrupp, A., Wetter, O. U., &#38; Höer, J. (2019). Influence of Elevated Intra-abdominal Pressure on Suture Tension Dynamics in a Porcine Model. <i>Journal of Surgical Research</i>, <i>233</i>, 207–212. <a href=\"https://doi.org/10.1016/j.jss.2018.07.043\">https://doi.org/10.1016/j.jss.2018.07.043</a>"},"abstract":[{"lang":"eng","text":"Background: Inadequate suture tension is a risk factor for the failure of laparotomy closure.\r\nSuture tension dynamics in the abdominal wall are still obscure due to the lack of\r\nmeasuring devices. To answer the questions if intra-abdominal hypertension (IAH) influences\r\nsuture tension in midline laparotomies and if IAH leads to a permanent loss of\r\nsuture tension, microsensors were applied in a porcine model of IAH.\r\nMaterial and methods: Microsensors measuring suture tension “on the thread” with a frequency\r\nof 1/s were developed and implanted in the suture lines of midline laparotomies in\r\nfour pigs. During a 23-h experiment under general anesthesia, two intervals of IAH (30 mm\r\nHg) were applied, interrupted by a 3-h interval without elevated intra-abdominal pressure.\r\nResults: All sensors showed an immediate and reproducible response to changes of intraabdominal\r\npressure. The two 9-h periods of IAH resulted in a significant elevation of suture\r\ntension (P¼0.003 and P¼0.0009, respectively). Reducing the IAH lead to a significant loss\r\nof suture tension (P¼0.0005andP¼0.0001, respectively). After the second interval with IAH, a\r\ncomplete loss of mean suture tension was observed. A statistically significant “recovery” of\r\nsuture tension in the interval between the two phases with IAH was not observed.\r\nConclusions: Intervals with elevated intra-abdominal pressure have a direct influence on\r\nsuture tension in midline laparotomy wounds. Intervals with IAH lead to a significant loss\r\nof suture tension in the suture line and to a complete loss of mean suture tension at the\r\nend of this experiment. A subsequent gaping of the fascia might contribute to either acute\r\nor chronic failure of laparotomy closure"}],"volume":233,"language":[{"iso":"eng"}]}